Growth Factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation and cellular differentiation. Usually it is a protein or a steroid hormone. Growth factors are important for regulating a variety of cellular processes.
Read more about Growth Factor.
Some articles on growth factor:
... For the last two decades, growth factors have been increasingly used in the treatment of hematologic and oncologic diseases and cardiovascular diseases like neutropenia myelodysplastic syndrome (MDS ...
... transport • signal transduction • epidermal growth factor receptor signaling pathway • cellular membrane organization • endosomal transport • negative ... HGS/HRS (hepatocyte growth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein ...
... to suppress sustained activation of ERK1/2 and c-met by the heparin binding growth factors (HB-GF), fibroblast growth factor (FGF) and hepatocyte growth factor (HGF), thereby ... As a review, HGF, or scatter factor, activates its receptor c-Met which activates mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and PI3K ... The HGF/c-Met axis mediates the invasive growth phenotype necessary for metastasis through coordination of cell motility and degradation of extracellular ...
... with binding sites for many transcription factors including AP1, ATF, E2F, HNF3b, NF1, NFκB, SP1, and SRF, and 2 poly(CA) stretches that may form Z-DNA ... including stimulation by platelet-derived growth factor and basic fibroblast growth factor, transforming growth factor β1 (TGF-β1), growth hormone, the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA ...
... tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles ... this gene is transiently upregulated in response to fibroblast growth factor two ... autonomous inhibitory effect on fibroblast growth factor two signaling ...
Famous quotes containing the words factor and/or growth:
“It is change, continuing change, inevitable change, that is the dominant factor in society today. No sensible decision can be made any longer without taking into account not only the world as it is, but the world as it will be.... This, in turn, means that our statesmen, our businessmen, our everyman must take on a science fictional way of thinking.”
—Isaac Asimov (1920–1992)
“The wind of change is blowing through the continent. Whether we like it or not, this growth of national consciousness is a political fact.”
—Harold MacMillan (1894–1986)