Tumor Lysis Syndrome

In medicine (oncology and hematology), tumor lysis syndrome (TLS, alternative spelling tumour lysis syndrome) is a group of metabolic complications that can occur after treatment of cancer, usually lymphomas and leukemias, and sometimes even without treatment. These complications are caused by the break-down products of dying cancer cells and include hyperkalemia, hyperphosphatemia, hyperuricemia and hyperuricosuria, hypocalcemia, and consequent acute uric acid nephropathy and acute renal failure.

Read more about Tumor Lysis SyndromeCause and Risk Factors, Symptoms and Pathogenesis, Diagnosis, Prevention, Treatment

Other articles related to "tumor lysis syndrome":

Tumor Lysis Syndrome - Treatment
... Acute renal failure prior to chemotherapy ... Since the major cause of acute renal failure in this setting is uric acid build-up, therapy consists of rasburicase to wash out excessive uric acid crystals as well as a loop diuretic and fluids ...
Allopurinol - Uses - Tumor Lysis Syndrome
... also commonly used in chemotherapeutic treatments to treat 'tumor lysis syndrome' (as these regimes can rapidly produce severe acute hyperuricemia) although it has gradually been replaced by urate oxidase therapy ...

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    [T]he syndrome known as life is too diffuse to admit of palliation. For every symptom that is eased, another is made worse. The horse leech’s daughter is a closed system. Her quantum of wantum cannot vary.
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