Effects of Supplementation
To date, orexin-A has shown no negative side effects. Positive side effects include an improvement in cognitive ability and functionality in a sleep deprived state. Taking orexin-A also increases arousal, alertness, attention, and muscle tone. Orexin-A has no effect on subjects who are well rested. The most important side effect orexin-A is thought to have is counteracting the effects of narcolepsy.
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“Trade and commerce, if they were not made of India-rubber, would never manage to bounce over the obstacles which legislators are continually putting in their way; and, if one were to judge these men wholly by the effects of their actions and not partly by their intentions, they would deserve to be classed and punished with those mischievous persons who put obstructions on the railroads.”
—Henry David Thoreau (1817–1862)
“Trade and commerce, if they were not made of India-rubber, would never manage to bounce over the obstacles which legislators are continually putting in their way; and, if one were to judge these men wholly by the effects of their actions and not partly by their intentions, they would deserve to be classed and punished with those mischievous persons who put obstructions on the railroads.”
—Henry David Thoreau (1817–1862)