Orbitofrontal Cortex

The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes in the brain which is involved in the cognitive processing of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47 Because of its functions in emotion and reward, the OFC is considered by some to be a part of the limbic system.

The OFC anatomically is defined as the part of the prefrontal cortex that receives projections from the magnocellular, medial nucleus of the mediodorsal thalamus. It gets its name from its position immediately above the orbits in which the eyes are located. Considerable individual variability has been found in the OFC of both humans and non-human primates. A related area is found in rodents.


Read more about Orbitofrontal CortexFunctional Connectivity of The Orbitofrontal Cortex, Clinical Applications of OFC Connectivity Disruptions, Orbitofrontal Cortex and Addiction, Anatomy of OFC and Addiction, OFC and Addiction in Animal Studies, Neuroimaging Research in Healthy Participants, Consequences of Damage To The OFC

Other articles related to "orbitofrontal cortex, cortex":

Meta-analyses of Affective Neuroscience - Kober Et Al. 2008
... anterior insula/frontal operculum/right temporal pole/ posterior orbitofrontal cortex, the anterior insula/ posterior orbitofrontal cortex, the ventral anterior insula/ temporal cortex ... The third “Medial Prefrontal Cortex” group included the dorsal medial prefrontal cortex, pregenual anterior cingulate cortex, and rostral dorsal anterior cingulate cortex, which the authors discuss as ... Association” group included areas V8 and V4 of the primary visual cortex, the medial temporal lobe, and the lateral occipital cortex, and the sixth “Medial ...
Reward Dependence - Brain Physiology
... projections and Tracts between the prefrontal cortex predict our individual differences in reward processing, reward dependence and reward-guided behaviors ... greater the concentration of tissue in the orbitofrontal cortex (the outer strip of the brain just above the eyes), and in the ventral striatum (a deep ... lobes, the caudate Grey Matter Density (GMD) in the orbitofrontal cortex and the basal ganglia of the ventral striatum ...
Mind-blindness - Relevance & Causes - Biological Basis of Mind-Blindness
... The anterior paracingulate cortex (Brodmann), is considered at the key region of mentalizing ... corpus callosum and the anterior cingulate cortex ... This cortex is associated with the medial frontal cortex where activation is associated with the mentalization of states ...
Self-control Research - Brain Regions Involved in Self-control - Orbitofrontal Cortex
... Patients who have damage to the orbitofrontal cortex tend to make decisions on the basis of short-term rather than long term consequences, suggesting that this area is key to the exercise of self-c ...