Nucleic Acid

Nucleic Acid

Nucleic acids are large biological molecules essential for all known forms of life. They include DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Together with proteins, nucleic acids are the most important biological macromolecules; each is found in abundance in all living things, where they function in encoding, transmitting and expressing genetic information.

Nucleic acids were discovered by Friedrich Miescher in 1869. Experimental studies of nucleic acids constitute a major part of modern biological and medical research, and form a foundation for genome and forensic science, as well as the biotechnology and pharmaceutical industries.

Read more about Nucleic Acid:  Occurrence and Nomenclature, Molecular Composition and Size, Topology, Nucleic Acid Sequences

Other articles related to "nucleic acid, nucleic acids, acid, acids":

DNA Nanotechnology - History
... the DNA replication fork and the mobile Holliday junction, but Seeman's insight was that immobile nucleic acid junctions could be created by properly designing the strand sequences to ... on the synthesis of a cube made of DNA, the first synthetic three-dimensional nucleic acid nanostructure, for which he received the 1995 Feynman Prize in Nanotechnology ... An improved system, which was the first nucleic acid device to make use of toehold-mediated strand displacement, was demonstrated by Bernard Yurke ...
Helen M. Berman - Professional Career
... At Fox Chase, Berman became interested in nucleic acid structures and in bioinformatics ... In 1989, Berman moved to Rutgers and in 1992, along with other scientists, she co-founded the Nucleic Acid Database (NDB) to collect and disseminate information about nucleic acid ... At Rutgers, she continued to study nucleic acids, their interactions with proteins, and also researched the structure of collagen in collaboration with Barbara Brodsky and ...
Adaptor Hypothesis
... in DNA is used to specify the amino acid sequence of proteins ... He proposed that each amino acid is first attached to its own specific “adaptor” piece of nucleic acid (in an enzyme catalysed reaction) ... The order of assembly of the amino acids is then determined by a specific recognition between the adaptor and the nucleic acid which is serving as the informational template ...
Spin Column-based Nucleic Acid Purification
... Column-based nucleic acid purification is a solid phase extraction method to quickly purify nucleic acids ... This method relies on the fact that the nucleic acid may bind (adsorption) to the solid phase (silica or other) depending on the pH and the salt content of the buffer, which may be a Tris-EDTA (TE ... sample is added to the column and the nucleic acid binds due to the lower pH (relative to the silanol groups on the column) and salt concentration of the binding solution, which may contain ...
Types of Nucleic Acids - Artificial Nucleic Acid Analogs
... Artificial nucleic acid analogs have been designed and synthesized by chemists, and include peptide nucleic acid, morpholino- and locked nucleic acid, as well as glycol nucleic acid and ...