Mir-10 Micro RNA Precursor Family

Mir-10 Micro RNA Precursor Family

The miR-10 microRNA precursor is a short non-coding RNA gene involved in gene regulation. It is part of an RNA gene family which contains miR-10, miR-51, miR-57, miR-99 and miR-100. miR-10, miR-99 and miR-100 have now been predicted or experimentally confirmed in a wide range of species. (MIPF0000033, MIPF0000025) mir-51 and mir-57 have currently only been identified in the nematode Caenorhabditis elegans (MIPF0000268, MIPF0000271). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA.

Read more about Mir-10 Micro RNA Precursor Family:  Species Distribution, Genomic Location, MiR-10*, Pattern of Expression, Targets of MiR-10, Association With Cancer

Other related articles:

Mir-10 Micro RNA Precursor Family - Association With Cancer
... Recently there has been much interest in abnormal levels of expression of microRNAs in cancers ... Upregulation of miR-10 has been found in a number of cancers ...

Famous quotes containing the word family:

    English people apparently queue up as a sort of hobby. A family man might pass a mild autumn evening by taking the wife and kids to stand in the cinema queue for a while and then leading them over for a few minutes in the sweetshop queue and then, as a special treat for the kids, saying “Perhaps we’ve time to have a look at the Number Thirty-One bus queue before we turn in.”
    Calvin Trillin (b. 1940)