Meiome - Phases - Meiosis I - Metaphase I

Metaphase I

Homologous pairs move together along the metaphase plate: As kinetochore microtubules from both centrioles attach to their respective kinetochores, the homologous chromosomes align along an equatorial plane that bisects the spindle, due to continuous counterbalancing forces exerted on the bivalents by the microtubules emanating from the two kinetochores of homologous chromosomes. The physical basis of the independent assortment of chromosomes is the random orientation of each bivalent along the metaphase plate, with respect to the orientation of the other bivalents along the same equatorial line.

Read more about this topic:  Meiome, Phases, Meiosis I

Other articles related to "metaphase i, metaphase":

Metaphase in Cytogenetics and Cancer Studies
... The analysis of metaphase chromosomes is one of the main tools of classical cytogenetics and cancer studies ... Metaphase chromosomes make the classical picture of chromosomes (karyotype) ... in short term culture and arrested in metaphase using mitotic inhibitor ...
Transition From Prometaphase To Metaphase
... have attached to their kinetochores, upon which metaphase begins ... Early events of metaphase can coincide with the later events of prometaphase, as chromosomes with connected kinetochores will start the events of metaphase ... Interphase G1 phase S phase G2 phase M phase Mitosis (Preprophase Prophase Prometaphase Metaphase Anaphase Telophase) Cytokinesis Cell cycle checkpoints Restriction point Spindle ...
... formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed ... During cell division Demecolcine inhibits mitosis at metaphase by inhibiting spindle formation ... has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle ...