Lymphoma

Lymphoma is a cancer of the lymphocytes, a type of cell that forms part of the immune system. Typically, lymphoma is present as a solid tumor of lymphoid cells. Treatment might involve chemotherapy and in some cases radiotherapy and/or bone marrow transplantation, and can be curable depending on the histology, type, and stage of the disease. These malignant cells often originate in lymph nodes, presenting as an enlargement of the node (a tumor). It can also affect other organs in which case it is referred to as extranodal lymphoma. Extranodal sites include the skin, brain, bowels and bone. Lymphomas are closely related to lymphoid leukemias, which also originate in lymphocytes but typically involve only circulating blood and the bone marrow (where blood cells are generated in a process termed haematopoesis) and do not usually form static tumors. There are many types of lymphomas, and in turn, lymphomas are a part of the broad group of diseases called hematological neoplasms.

Thomas Hodgkin published the first description of lymphoma in 1832, specifically of the form named after him, Hodgkin's lymphoma. Since then, many other forms of lymphoma have been described, grouped under several proposed classifications. The 1982 Working formulation classification became very popular. It introduced the category non-Hodgkin lymphoma (NHL), divided into 16 different diseases. However, because these different lymphomas have little in common with each other, the NHL label is of limited usefulness for doctors or patients and is slowly being abandoned. The latest classification by the WHO (2008) lists 70 different forms of lymphoma divided in four broad groups.

Although older classifications referred to histiocytic lymphomas, these are recognized in newer classifications as of B, T or NK cell lineage. True histiocytic malignancies are rare and are classified as sarcomas.

Read more about Lymphoma:  Classification, Signs and Symptoms, Diagnosis, Etiology, Staging, Prognosis, and Treatment, Epidemiology, Comparison, Research Directions

Other articles related to "lymphoma, lymphomas":

Lymphoma - Research Directions
... research into the causes, prevalence, diagnosis, treatment, and prognosis of lymphoma is being performed ... In general, there are two types of lymphoma research clinical or translational research and basic research ... a suspected carcinogen can cause healthy cells to turn into lymphoma cells in the laboratory or how the DNA changes inside lymphoma cells as the disease progresses ...
Marginal Zone B-cell Lymphoma
... Marginal zone B-cell lymphoma is a type of B-cell lymphoma presenting primarily in the marginal zone ... There are three types Splenic marginal zone lymphoma Extranodal marginal zone B cell lymphoma (MALT lymphoma, or "mucosa-associated lymphoid tissue ...
Splenic Lymphoma With Villous Lymphocytes
... Splenic lymphoma with villous lymphocytes is a rare type of lymphoma that involves mature B cells ... Older names include lymphoma simulating hairy cell leukemia and lymphoplasmacytic lymphoma with circulating villous lymphocytes ... Whether this condition is identical to splenic marginal zone lymphoma, or only highly similar, is a matter of debate ...
Mixed-cell Lymphoma
... Mixed-cell lymphomas are lymphomas that have both large cells and small cells in them ... In MeSH, the phrase "mixed-cell lymphoma" is currently classified under non-Hodgkin lymphoma ...
List Of Cancer Types - L
... Cancer Liposarcoma Liver Cancer (Primary) Lung Cancer, Non-Small Cell Lung Cancer, Small Cell Lymphomas Lymphoma, AIDS-related Lymphoma, Burkitt Lymphoma, cutaneous T-Cell Lymphoma, Hodgkin Lymphomas, Non-Hod ...