IP Antibody

Immunoprecipitation - Technological Advances - Agarose - Preclearing
... some amount of non-specific binding to the IP antibody, Protein A/G or the beaded support will occur and negatively affect the detection of the immunoprecipitated target(s) ... binding of these components to the IP beads or antibody ... This approach, though, does not account for non-specific binding to the IP antibody, which can be considerable ...