GJB2 - Function

Function

Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1; MIM 304040) and CX26 (this protein) are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.

Read more about this topic:  GJB2

Other articles related to "functions, function":

Formal Definitions - Lebesgue Integral
... For instance, a sequence of functions can frequently be constructed that approximate, in a suitable sense, the solution to a problem ... Then the integral of the solution function should be the limit of the integrals of the approximations ... However, many functions that can be obtained as limits are not Riemann integrable, and so such limit theorems do not hold with the Riemann integral ...
Integral - Fundamental Theorem of Calculus
... is the statement that differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original ... integrals by using an antiderivative of the function to be integrated ...
Integral - Extensions - Multiple Integration
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance, a vector in R3 ... Just as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the ... via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between the surface and the plane.) If the number of ...

Famous quotes containing the word function:

    The press and politicians. A delicate relationship. Too close, and danger ensues. Too far apart and democracy itself cannot function without the essential exchange of information. Creative leaks, a discreet lunch, interchange in the Lobby, the art of the unattributable telephone call, late at night.
    Howard Brenton (b. 1942)

    The function of muscle is to pull and not to push, except in the case of the genitals and the tongue.
    Leonardo Da Vinci (1425–1519)

    The more books we read, the clearer it becomes that the true function of a writer is to produce a masterpiece and that no other task is of any consequence.
    Cyril Connolly (1903–1974)