Some articles on folding, folding intermediate:
Serine Protease Inhibitors - Serpins, Serpinopathies and Human Disease
... of data now suggest that the events associated with serpin polymerisation occur during the folding of the molecule, and that mutations that cause serpinopathies interfere ... In normal serpin folding, the serpin rapidly moves through a key folding intermediate to attain the native state ... Many studies have shown that it is the serpin folding intermediate that has the ability to polymerise, hence it is important that this folding species rapidly moves on to adopt native ...
... of data now suggest that the events associated with serpin polymerisation occur during the folding of the molecule, and that mutations that cause serpinopathies interfere ... In normal serpin folding, the serpin rapidly moves through a key folding intermediate to attain the native state ... Many studies have shown that it is the serpin folding intermediate that has the ability to polymerise, hence it is important that this folding species rapidly moves on to adopt native ...
Famous quotes containing the words intermediate and/or folding:
“Complete courage and absolute cowardice are extremes that very few men fall into. The vast middle space contains all the intermediate kinds and degrees of courage; and these differ as much from one another as men’s faces or their humors do.”
—François, Duc De La Rochefoucauld (1613–1680)
“There’s only one way for an individual to remain upright, not to fall to pieces, not to sink into the mire of self-oblivion ... or self-contempt. That’s calmly to turn away from everything, to say, “Enough!” and, folding one’s useless arms across one’s empty breast, to retain the ultimate, the sole attainable virtue, the virtue of recognizing one’s own insignificance.”
—Ivan Sergeevich Turgenev (1818–1883)
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