Some articles on folding, folding intermediate:
... of data now suggest that the events associated with serpin polymerisation occur during the folding of the molecule, and that mutations that cause serpinopathies interfere ... In normal serpin folding, the serpin rapidly moves through a key folding intermediate to attain the native state ... Many studies have shown that it is the serpin folding intermediate that has the ability to polymerise, hence it is important that this folding species rapidly moves on to adopt native ...
Famous quotes containing the words intermediate and/or folding:
“Complete courage and absolute cowardice are extremes that very few men fall into. The vast middle space contains all the intermediate kinds and degrees of courage; and these differ as much from one another as mens faces or their humors do.”
—François, Duc De La Rochefoucauld (16131680)
“Theres only one way for an individual to remain upright, not to fall to pieces, not to sink into the mire of self-oblivion ... or self-contempt. Thats calmly to turn away from everything, to say, Enough! and, folding ones useless arms across ones empty breast, to retain the ultimate, the sole attainable virtue, the virtue of recognizing ones own insignificance.”
—Ivan Sergeevich Turgenev (18181883)