Deep brain stimulation (DBS) is a surgical treatment involving the implantation of a medical device called a brain pacemaker, which sends electrical impulses to specific parts of the brain. DBS in select brain regions has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders such as chronic pain, Parkinson's disease, tremor and dystonia. Despite the long history of DBS, its underlying principles and mechanisms are still not clear. DBS directly changes brain activity in a controlled manner, its effects are reversible (unlike those of lesioning techniques) and is one of only a few neurosurgical methods that allows blinded studies.
The Food and Drug Administration (FDA) approved DBS as a treatment for essential tremor in 1997, for Parkinson's disease in 2002, and dystonia in 2003. DBS is also routinely used to treat chronic pain and has been used to treat various affective disorders, including major depression. While DBS has proven helpful for some patients, there is potential for serious complications and side effects.
Other articles related to "deep brain stimulation, brain, stimulation":
... The support for the use of deep brain stimulation in treatment-resistant depression comes from a handful of case studies, and this treatment is still in a very early investigational stage ...
... side of the body (opposite the side of the brain surgery), but bilateral pallidotomy was found to cause irreversible deterioration in speech and cognition ... two other potential rapidly evolving surgical approaches to Parkinson's disease such as deep brain stimulation (DBS) and restorative therapies ... Stimulation of portions of the Thalamus or lesioning has been used for various psychiatric and neurological conditions, and when practiced for movement disorders the target is in the motor nuclei ...
... Because the brain can shift slightly during surgery, there is the possibility that the electrodes can become displaced or dislodged ... may also be complications of surgery, such as bleeding within the brain ... After surgery, swelling of the brain tissue, mild disorientation and sleepiness are normal ...
... Deep brain stimulation is a surgical technique used to alleviate patients from phantom limb pain ... to surgery, patients undergo functional brain imaging techniques such as PET scans and functional MRI to determine an appropriate trajectory of where pain is originating ... electrode with four contact points was placed on the brain ...
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