DCF is a three-letter acronym that may stand for:
- Dach Centre Focus, a type of binoculars (dach is German for roof)
- Dallas Christmas Festival
- Dansk Cyklist Forbund, the Danish bicycle association
- Data clarification form in clinical trials
- DCF77 a longwave time signal and standard-frequency radio station in Germany.
- Debt cash flow
- Deoxycoformycin, an anti-neoplastic drug also known as pentostatin
- Department of Children & Families in the state of Florida
- Deputy Conservator of Forests, an officer in the Indian Forest Service
- Design rule for Camera File system, a specification for digital cameras
- Designation Challenge Fund for English museums
- Device Configuration File, an element of CANopen, an embedded-systems communication protocol and device profile specification
- Dichlorofluorescein, a fluorescent dye
- The theory of differentially closed fields
- Discounted cash flow
- Distributed Control Framework, a Java software framework for robots
- Disk Copy Fast, a floppy-disk software utility
- Dispersion compensating fibre
- Distributable cash flow
- Distributed Coordination Function, a technique used in Wi-Fi wireless LANs
- Document Composition Facility, a software package from IBM that handles and formats documents
- Double-clad fiber
- DRM Content Format, one of the Open Mobile Alliance (OMA DRM) specifications (Format of the preloaded contents distributed with nokia phones)
- The IATA airport code for Canefield Airport, Roseau, Dominica