Circular Dichroism

Circular Dichroism

Circular dichroism (CD) refers to the differential absorption of left and right circularly polarized light. This phenomenon was discovered by Jean-Baptiste Biot, Augustin Fresnel, and Aimé Cotton in the first half of the 19th century. It is exhibited in the absorption bands of optically active chiral molecules. CD spectroscopy has a wide range of applications in many different fields. Most notably, UV CD is used to investigate the secondary structure of proteins. UV/Vis CD is used to investigate charge-transfer transitions. Near-infrared CD is used to investigate geometric and electronic structure by probing metal d→d transitions. Vibrational circular dichroism, which uses light from the infrared energy region, is used for structural studies of small organic molecules, and most recently proteins and DNA.

Read more about Circular DichroismApplication To Biological Molecules, Experimental Limitations

Other articles related to "circular dichroism":

Circular Dichroism - Experimental Limitations
... At the quantum mechanical level, the information content of circular dichroism and optical rotation are identical ...
Circular Polarization - Circular Dichroism
... Circular dichroism (CD) is the differential absorption of left- and right-handed circularly polarized light ... Circular dichroism is the basis of a form of spectroscopy that can be used to determine the optical isomerism and secondary structure of molecules ... As a consequence, circular dichroism is exhibited by most biological molecules, because of the dextrorotary (e.g ...
Experimental Techniques For Studying Protein Folding - Circular Dichroism
... Circular dichroism is one of the most general and basic tools to study protein folding ... Circular dichroism spectroscopy measures the absorption of circularly polarized light ...

Famous quotes containing the word circular:

    Whoso desireth to know what will be hereafter, let him think of what is past, for the world hath ever been in a circular revolution; whatsoever is now, was heretofore; and things past or present, are no other than such as shall be again: Redit orbis in orbem.
    Sir Walter Raleigh (1552–1618)