Carnitine

Carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine. In living cells, it is required for the transport of fatty acids from the cytosol into the mitochondria during the breakdown of lipids (fats) for the generation of metabolic energy. It is widely available as a nutritional supplement. Carnitine was originally found as a growth factor for mealworms and labeled vitamin Bt. Carnitine exists in two stereoisomers: Its biologically active form is -carnitine, whereas its enantiomer, -carnitine, is biologically inactive.

Other articles related to "carnitine":

Sigma-Tau - From The 1970s To Today
... With the discovery in the 1970s of carnitine deficiency syndrome, an illness with a fatal outcome, Sigma-Tau focused the investigative efforts of its ... This was to bring about the creation of L-carnitine, one of the few Italian pharmaceutical products widely received outside Italy, and which was recognized by the United ... The chemical and biologic pharmacology study of carnitine, a substance of natural origin, enabled greater understanding of its efficacy in correcting the biochemical and metabolic defects at the base of ...
Carnitine O-acetyltransferase
... In enzymology, a carnitine O-acetyltransferase (CRAT, or CAT) (EC 2.3.1.7) is an enzyme that catalyzes the chemical reaction acetyl-CoA + carnitine CoA + O-acetylcarnitine Thus, the two substrates of ... Other names in common use include acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, carnitine acetyl coenzyme A transferase, carnitine acetylase ...
Chronic Fatigue Syndrome Treatment - Complementary and Alternative Medicine - Dietary Supplements - Carnitine
... L-Carnitine is an amino acid which includes ALC, a group of natural compounds that have an important role in cellular function ... Two RCTs found benefit from dietary supplementation with L-carnitine or its esters. 6 months trial on 96 aged subjects with CFS symptoms administering Acetyl L Carnitine was reported ...
CROT (gene)
... Peroxisomal carnitine O-octanoyltransferase is an enzyme that in humans is encoded by the CROT gene ... Carnitine octanoyltransferase (EC 2.3.1.137) is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and ... the function, structural features, and phylogenetics of human carnitine acyltransferase genes, including CROT ...
Carnitine - Sources - Other Sources
... Products containing -carnitine cannot be marketed as "natural health products" in Canada ... -Carnitine products and supplements are not allowed to be imported into Canada (Health Canada) ... government has issued an amendment in December 2011 allowing the sale of -carnitine without a prescription ...