Canavan Disease

Canavan disease, also called Canavan-Van Bogaert-Bertrand disease, aspartoacylase deficiency or aminoacylase 2 deficiency, is an autosomal recessive degenerative disorder that causes progressive damage to nerve cells in the brain. Canavan disease is also one of the most common degenerative cerebreal diseases of infancy. This disease is one of a group of genetic disorders called leukodystrophies.

Leukodystrophies are characterized by degeneration of myelin in the phospholipid layer insulating the axon of a neuron. The gene associated with the disorder is located on human chromosome 17.

Read more about Canavan DiseasePrevalence, Pathophysiology, Symptoms, Treatment, Prognosis, Current Research

Other articles related to "canavan disease":

Canavan Disease - Current Research
... The defective enzyme in Canavan disease, aspartoacylase, converts N-acetylaspartate into aspartate and acetate ...

Famous quotes containing the word disease:

    The peace loving nations must make a concerted effort in opposition to those violations of treaties and those ignorings of humane instincts which today are creating a state of international anarchy and instability from which there is no escape through mere isolation or neutrality.... When an epidemic of physical disease starts to spread, the community approves and joins in a quarantine of the patients in order to protect the health of the community against the spread of the disease.
    Franklin D. Roosevelt (1882–1945)