Ar Inhibitors

Treatment For Galactosemia and The Galactosemic Cataract
... Aldose reductase inhibitors, such as sorbinil, have also proven promising in preventing and reversing galactosemic cataracts ... AR inhibitors hinder aldose reductase from synthesizing galactitol in the lens, and thus restricts the osmotic swelling of the lens fibers ... Other AR inhibitors include the acetic acid compounds zopolrestat, tolrestat, alrestatin, and epalrestat ...