Uru or URU may refer to:
- Uru (boat), an ancient trading vessel
- Uru, Iran, a village in Razavi Khorasan Province, Iran
- Uru, São Paulo, a city in Brazil
- Uru (The Lion King), a fictional lioness character
- Uruguay, a country in southeastern South America (ISO 3166-1 alpha-3 country code: URU)
- Uru people, a group of pre-Incan people who live in Peru and Bolivia
- URU, a determinative in mesopotamian cuneiform script, see cities of the ancient Near East
- Mekanika Uru, a submachine gun
- Uru: Ages Beyond Myst, a computer game
- Myst Online: Uru Live, an online version of the original game
- Uru, the fictional metal in Marvel Comics, from which Thor's hammer Mjolnir is made
- Uru Uru Lake, a lake south of the Bolivian town of Oruro
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