Trpr

Some articles on trpr:

Corepressor - Function - Prokaryotes
... coli tryptophan repressor (TrpR) is only able to bind to DNA and repress transcription of the trp operon when its corepressor tryptophan is bound to it ... TrpR in the absence of tryptophan is known as an aporepressor and is inactive in repressing gene transcription ... Hence TrpR provides a negative feedback mechanism that regulates the biosynthesis of tryptophan ...
Tryptophan Repressor - Mechanism
... the amino acid tryptophan is in plentiful supply in the cell, trpR binds 2 molecules of tryptophan, which alters its structure and dynamics so that it becomes able to bind to operator DNA ... trpR also controls the regulation of its own production, through regulation of the trpR gene ...