SXM may refer to:
As an abbreviation:
- SXM (computational model), model for a Stream X-Machine
- SXM (transactional memory), a software under development at Microsoft Research
- Scanning X-ray Microscope (SXM), a chemical analysis method
- Starbury SXM, a basketball shoe also called an SXM
- SxM (album), a 1994 album by hip-hop band Sangue Misto
- SxM (SAM, SCM, SEM, etc.), formats of scanning microscope image handled by Image SXM
sxm, suffix of math files from StarOffice's StarMath (version 1–7)sxm, suffix of math files from OpenOffice.org XML (version 1)
As a code:
- Princess Juliana International Airport, Sint Maarten, island of Saint Martin, IATA code SXM
- Sint Maarten, ISO 3166-1 alpha-3 code SXM
- Sint Maarten national football team, FIFA code SXM
- Servicios Aéreos Especializados Mexicanos, airline based in Mexico, ICAO code SXM