Surface-enhanced Laser Desorption/ionization (SELDI)
The surface-enhanced laser desorption/ionization (SELDI) variant is similar to MALDI, but uses a biochemical affinity target. The technique known as surface-enhanced neat desorption (SEND) is a related variant of MALDI with the matrix is covalently linked to the target surface. The SELDI technology was commercialized by Ciphergen Biosystems in 1997 as the ProteinChip system. It is now produced and marketed by Bio-Rad Laboratories.
Read more about this topic: Soft Laser Desorption, Variants