Characters
- Sherlock Hound (J: Taichirō Hirokawa, E: Larry Moss): Just like his original incarnation, he has a genius intellect and is extremely knowledgeable in multiple fields. He keeps a cool and logical head despite the situation. Unlike his original incarnation, his only drug habit is smoking a tobacco pipe. He keeps his apartment a mess and is regularly conducting chemical experiments that lead to clouds of noxious fumes. He also seems to have feelings for Mrs. Hudson, as does the rest of the male cast. Hound resembles a red fox.
- Doctor Watson (J: Kōsei Tomita, E: Lewis Arquette): Hound's loyal companion, he is a trained doctor who returned to England shortly before meeting Hound. He tries his best to help Hound as he can, but has difficulty at times keeping up with Hound, both mentally and physically, being a bit overweight. Watson is a Scottish terrier.
- Marie Hudson (J: Yōko Asagami, E: Patricia Parris): Hound and Watson's landlady. In most adaptations, Holmes' long-suffering landlady is shown as middle-aged or older, but in this version she is a widow in her 20s and a love interest of many, including Holmes and Moriarty (mostly Holmes), and given the first name Marie. Her late husband Jim was a pilot and Hound finds her contacts in the world of aviation useful. She can also be quite quick and resourceful when need be, and she also appears to be a crack shot with a revolver. Miyazaki actually wanted to present her as the real brains of Baker Street, running rings around both Hound and his enemy Moriarty, but he was overruled. Like many people in Hound's world, Mrs. Hudson is a golden retriever.
- Professor Moriarty (J: Chikao Ōtsuka, E: Hamilton Camp): Unlike the rarely appearing mafia donnish Moriarty in the books, this Moriarty is portrayed as working personally on his plans without any sort of support network and frequently encountering Hound and his allies, being the antagonist in the majority of the episodes. Still an intellectual, he is a master inventor, often the one responsible for the steam punk technology seen in the show, including his personal "steam car", which is more like a cross between a tractor and a tank than a car. His plans can occasionally be very complex or outlandish that rely on one questioning or linking together unusual acts, which is often how Hound figures out what Moriarty is up to. In this version, Moriarty resembles a gray wolf.
- Smiley and George/Todd (J: Hiroshi Masuoka (George/Todd) & Mitsuo Senda (Smiley), E: Larry Moss (George/Todd) and Lewis Arquette (Smiley): Moriarty's henchmen, created for the show. Smiley is tall, lanky, has something of a limited intellect, a thick Cockney accent and a positive attitude. In the episodes directed by Hayao Miyazaki, he is colored a pea green, while in other episodes, he's medium brown. George/Todd is small and squat, has a negative outlook on the situation, and is usually the first to criticize Moriarty or his plans. He is inconsistently called either George or Todd, sometimes within a single episode, early in the series, eventually settling on Todd. The two are often used for comic relief. Before they worked for Moriarty, they were members of the Bengal Pirates that appeared in the first episode, though they escaped being arrested with the rest of the crew. This was indeed them, because Smiley remarks in the second episode that they used to be Pirates.
- Inspector Lestrade (J: Shōzō Iizuka), E: Lewis Arquette): As Hound's go-to guy in the police force, he's also the first to call on Hound for assistance on a case. A well-meaning and passionate police officer, he's not the most attentive of people, and his hotheaded and impulsive nature can lead to his landing in comedic situations. Lestrade is a bull dog.
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“What makes literature interesting is that it does not survive its translation. The characters in a novel are made out of the sentences. Thats what their substance is.”
—Jonathan Miller (b. 1936)