Serum Sickness

Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 4–10 days after exposure. It is a type of hypersensitivity, specifically immune complex hypersensitivity (type III). The term serum sickness–like reaction (SSLR) is occasionally used to refer to similar illnesses that arise from the introduction of certain non-protein substances. It was first characterized by Clemens von Pirquet and Béla Schick in 1906.

Read more about Serum SicknessCauses, Symptoms, Diagnosis, Treatment, Prevention, See Also

Other articles related to "serum sickness, serum":

Serum Sickness - See Also
... Hypersensitivity Arthus reaction Serum sickness-like reaction. ...
Immunosuppressive Drug - Antibodies - Polyclonal Antibodies
... Heterologous polyclonal antibodies are obtained from the serum of animals (e.g ... there are two preparations available to the market Atgam, obtained from horse serum, and Thymoglobuline, obtained from rabbit serum ... to a point where there is no longer a risk of serum sickness ...
Serum Sickness-like Reaction
... Serum sickness-like reactions refer to adverse reactions that have similar symptoms to serum sickness, but in which immune complexes are not found ...
Serum Sickness-like Reaction - Pathogenesis
... Serum sickness-like reaction is named for its clinical similarity to serum sickness, in which immune complexes are deposited in the skin, joints, and other organs ... True serum sickness, a type III hypersensitivity reaction, results in fever, lymphadenopathy, arthralgias,cutaneous eruptions, gastrointestinal ... In contrast, serum sickness-like reactions are specific drug reactions that are not associated with circulating immune complexes ...
Serum Sickness-like Reaction - Diagnosis
... Case reports have noted the absence of fever in serum sickness-like reactions to amoxicillin ... Significant decreases in serum C3, C4, and CH50, reported in the literature for true serum sickness, are rarely described in serum sickness-like reaction ...

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