Phosphatidylinositol

Phosphatidylinositol consists of a very large family of complex compounds as illustrated on the right. They are negatively charged due to the phospholipid and a minor component in the cytosolic side of eukaryotic cell membranes. The specific lipid chains are typically not identified and the specific isomer of the nine possible isomers of inositol is not specified.

The specific phosphatidylinositol using the isomer, muco-inositol is used as a sensory receptor in the gustatory modality of the sensory system. It is typically identified as PtdIns in the sensory literature.

The other forms of phosphatidylinositol are commonly addressed as PI in the more general biochemical literature.

The phosphatidylinositol can be phosphorylated to form phosphatidylinositol phosphate (PIP), phosphatidylinositol bisphosphate (PIP2) and phosphatidylinositol trisphosphate (PIP3). PIP, PIP2 and PIP3 are collectively called phosphoinositides.

Read more about PhosphatidylinositolBiosynthesis, Chemistry, Phosphoinositides

Other articles related to "phosphatidylinositols, phosphatidylinositol":

Phosphoinositide-dependent Kinase-1 - Etymology
... with membrane phospholipids including phosphatidylinositols, phosphatidylinositol (3,4)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate ... indirectly regulates PDPK1 by phosphorylating phosphatidylinositols which in turn generates phosphatidylinositol (3,4)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate ... However, PDPK1 is believed to be constitutively active and does not always require phosphatidylinositols for its activities ...
Phosphatidylinositol - Phosphoinositides
... Phosphorylated forms of phosphatidylinositol (PI)are called phosphoinositides and play important roles in lipid signaling, cell signaling and membrane trafficking ... Phosphatidylinositol monophosphates Phosphatidylinositol 3-phosphate, also known as PtdIns3P or PI(3)P Phosphatidylinositol 4-phosphate, also known as PtdIns4P or PI(4)P Phosphatidylinositol 5-phosphate ...
PIP4K2B
... function • receptor signaling protein activity • ATP binding • 1-phosphatidylinositol-4-phosphate 5-kinase activity • 1-phosphatidylinositol-5-phosphate 4-kinase activity Cellular ... The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosp ... This gene is a member of the phosphatidylinositol-4-phosphate 5-kinase family ...
PLCB3
... Gene EC number 3.1.4.11 Gene Ontology Molecular function • phosphatidylinositol phospholipase C activity • phospholipase C activity • signal ... of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate ...
CDIPT
... Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth ... Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol ... Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of ...