Peptide Loading

Some articles on peptides, peptide loading, peptide:

Tapasin - Function
... antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane ... This interaction facilitates optimal peptide loading on the MHC class I molecule ... Tapasin is one component of the peptide-loading complex, and can be found associated with MHC class I molecules after the MHC class I heavy chain has associated with Beta2 ...
MHC Class I - Translocation and Peptide Loading
... The peptide translocation from the cytosol into the lumen of the ER is accomplished by the transporter associated with antigen processing (TAP) ... The two subunits form a peptide binding site and two ATP binding sites that face the lumen of the cytosol ... TAP binds peptides on the cytoplasmic site and translocates them under ATP consumption into the lumen of the ER ...

Famous quotes containing the word loading:

    Nitrates and phosphates for ammunition. The seeds of war. They’re loading a full cargo of death. And when that ship takes it home, the world will die a little more.
    Earl Felton, and Richard Fleischer. Captain Nemo (James Mason)