Operculum may refer to:
In human biology:
- Operculum (in pregnancy), the cervical mucus plug that blocks the cervix of the uterus after conception
- Operculum (brain), the part of the brain covering the insula
- Operculum (dentistry), a small flap of tissue which may cover an erupting or partially erupted molar
In animal biology:
- Operculum (animal), a structure resembling a lid or a small door that opens and closes
- Operculum (fish), a flap of the bony fish covering the gills
- Operculum (gastropod), a lid on the shell of some gastropods
- Operculum (bird), a structure which covers the nares of some birds
- Operculum (bryozoa), a lid on the orifice of some bryozoans
In botany:
- Operculum (botany), various lids and flaps pertaining to plants, algae and fungi
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