Nucleotide exchange factors (NEFs) are proteins that stimulate the exchange (replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins.
Read more about Nucleotide Exchange Factor: Function
Other articles related to "nucleotide exchange factor, factor, nucleotide exchange factors, nucleotide, exchange, nucleotides":
... SH3/SH2 adaptor activity • guanyl-nucleotide exchange factor activity • GTPase activator activity • epidermal growth factor receptor binding • protein binding • phospholipid binding • Rac guanyl-nucle ... The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements ... and it associates maximally with the nucleotide-free states of these GTPases ...
... Nucleotide exchange factors actively assist in the exchange of depleted nucleoside diphosphates for fresh nucleoside triphosphates ... NEFs are specific for the nucleotides they exchange (ADP or GDP, but not both) and are often specific to a single protein or class of proteins with which they interact ...
49414 GeneCards ARHGEF4 Gene Gene Ontology Molecular function • guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor ...
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