MMP9

MMP9

Identifiers Symbols MMP9; CLG4B; GELB; MANDP2; MMP-9 External IDs OMIM: 120361 MGI: 97011 HomoloGene: 3659 ChEMBL: 321 GeneCards: MMP9 Gene EC number 3.4.24.35

Gene Ontology
Molecular function	• fibronectin binding • metalloendopeptidase activity • protein binding • collagen binding • zinc ion binding • protein complex binding • metal ion binding
Cellular component	• extracellular region • proteinaceous extracellular matrix • extracellular space • protein complex
Biological process	• skeletal system development • ossification • response to hypoxia • proteolysis • response to oxidative stress • embryo implantation • response to radiation • response to heat • response to mechanical stimulus • cell growth • transformation of host cell by virus • extracellular matrix disassembly • extracellular matrix organization • macrophage differentiation • collagen catabolic process • positive regulation of synaptic plasticity • response to estradiol stimulus • response to lipopolysaccharide • response to retinoic acid • response to vitamin A • response to tumor necrosis factor • response to nicotine • response to drug • positive regulation of apoptotic process • response to ethanol • positive regulation of angiogenesis • tissue remodeling • positive regulation of keratinocyte migration • response to hyperoxia • anatomical structure regression • cellular response to interleukin-1 • cellular response to low-density lipoprotein particle stimulus • cellular response to cell-matrix adhesion
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4318 17395 Ensembl ENSG00000100985 ENSMUSG00000017737 UniProt P14780 P41245 RefSeq (mRNA) NM_004994.2 NM_013599.2 RefSeq (protein) NP_004985.2 NP_038627.1 Location (UCSC) Chr 20:
44.64 – 44.65 Mb Chr 2:
164.94 – 164.96 Mb PubMed search

Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is an enzyme that in humans is encoded by the MMP9 gene.