Natural History
The natural history of mitral stenosis secondary to rheumatic fever (the most common cause) is an asymptomatic latent phase following the initial episode of rheumatic fever. This latent period lasts an average of 16.3 ± 5.2 years. Once symptoms of mitral stenosis begin to develop, progression to severe disability takes 9.2 ± 4.3 years.
In individuals who were offered mitral valve surgery but refused, survival with medical therapy alone was 44 ± 6% at 5 years, and 32 ± 8% at 10 years after they were offered correction.
Read more about this topic: Mitral Valvuloplasty
Famous quotes containing the words natural and/or history:
“Knowledge has two extremes. The first is the pure natural ignorance in which all men find themselves at birth. The other extreme is that reached by great minds, who, having run through all that men can know, find they know nothing, and come back again to that same natural ignorance from which they set out; this is a learned ignorance which is conscious of itself.”
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“In front of these sinister facts, the first lesson of history is the good of evil. Good is a good doctor, but Bad is sometimes a better.”
—Ralph Waldo Emerson (1803–1882)