Photosensitivity
Photosensitivity is a known symptom of lupus, but its relationship to and influence on other aspects of the disease remain to be defined. Causes of photosensitivity may include:
- change in autoantibody location
- cytotoxicity
- inducing apoptosis with autoantigens in apoptotic blebs
- upregulation of adhesion molecules and cytokines
- inducing nitric oxide synthase expression
- ultraviolet-generated antigenic DNA.
Tumor necrosis factor alpha also seems to play a role in the development of photosensitivity.
Read more about this topic: Lupus Erythematosus, Symptoms
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