Lipkin (Hebrew: ליפקין, Russian: Липкин) is a surname and may refer to:
- Amnon Lipkin-Shahak
- Avi Lipkin (born 1949), American-born Israeli author and conspiracy theorist
- Dmitry Lipkin, a television writer and playwright
- Harry (Zvi) Jeannot Lipkin (born 1921), an Israeli theoretical physicist
- Heather Slade-Lipkin, an English pianist, harpsichordist and teacher
- Mariya Lipkina
- Nikolay Lipkin
- Randie Lipkin
- Steven Barry Lipkin (born 1942, Brooklyn, New York), an American songwriter and record producer
- W. Ian Lipkin (born 1952), the John Snow Professor of Epidemiology at the Mailman School of Public Health
- Yisrael Lipkin Salanter
- Lipkin Gorman v Karpnale Ltd
- Peaucellier–Lipkin linkage, named after Yom Tov Lipman Lipkin