Izzy is a common nickname for the given names Israel, Elizabeth, Isaac, Isambard, Isidore, Isabel, Isabella, Ismail, Izebel, or Izmara. It may also refer to:

  • Izzy (mascot), the 1996 Summer Olympics mascot
  • Izzy Alcántara, a Baseball player
  • Izzy Gomez (TUGS), in the series TUGS
  • Izzy Izumi, in the Digimon series
  • Izzy Lang, American football running back
  • Izzy Sinclair, in the Doctor Who comic book
  • Izzy Sparks, a video game character
  • Izzy Stradlin, former Guns N' Roses guitarist
  • Isabelle Hoyland, a character in the Australian soap opera Neighbours
  • Isobel Cooper, a soprano known professionally as Izzy
  • Izzie Stevens, in the series Grey's Anatomy
  • Jason Isringhausen, a baseball player
  • Izzy one of the 22 contestants in Total Drama Island
  • Isabel "Izzy" Reubens, a character in Love and Rockets
  • Isadora Duncan Dance Awards
  • Izzy Daniels, the main character of the television movie Jump In!
  • Izzy, the informant for Sonny and Rico in Miami Vice
  • Isabella "Izzy" Lirag, the great-grand daughter of textile business tycoon, Don Basilio Lirag of Lirag Textile Mills'