Immune Tolerance

Immune tolerance or immunological tolerance is the process by which the immune system does not attack an antigen. It can be either 'natural' or 'self tolerance', in which the body does not mount an immune response to self antigens, or 'induced tolerance', in which tolerance to external antigens can be created by manipulating the immune system. It occurs in three forms: central tolerance, peripheral tolerance and acquired tolerance.

Genetic defects in these processes lead to autoimmunity, such as in Autoimmune polyendocrine syndrome type 1 (APS-1) and immunodysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX).

Read more about Immune Tolerance:  Central Tolerance, Peripheral Tolerance, Acquired Tolerance, Immune Tolerance To Allografts

Other articles related to "immune tolerance, immune, tolerance":

Immune Tolerance To Allografts
... cells or tissue are grafted to a so-called privileged site that is sequestered from immune surveillance ... The second is when a state of tolerance has been induced biologically, usually by previous exposure to the antigen of the donor in a manner that cause ...
Tolerance - Biology, Medicine, Physiology
... Desiccation tolerance, the ability of an organism to endure extreme dryness Drug tolerance or physiological tolerance, a decrease in the response to a substance due to previous exposure ...
B Cell - Immune Tolerance
... B cells are tested for auto-reactivity by the immune system before leaving the bone marrow ... In the bone marrow (the central lymphoid organ), central tolerance is produced ...
Frank Macfarlane Burnet - Walter and Eliza Hall Institute - Immunology
... defined during its embryogenesis through complex interactions between immune cells and all the other cells and molecules within an embryo ... (autoimmunity) and by extension the idea of immune tolerance ... provided the experimental basis for inducing immune tolerance, thereby allowing the transplantation of solid organs ...

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