HRAS

HRAS

Identifiers Symbols HRAS; C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; K-RAS; N-RAS; RASH1 External IDs OMIM: 190020 MGI: 96224 HomoloGene: 55890 ChEMBL: 2167 GeneCards: HRAS Gene

Gene Ontology
Molecular function GTPase activity
protein binding
GTP binding
protein C-terminus binding
Cellular component Golgi membrane
nucleus
cytoplasm
Golgi apparatus
cytosol
plasma membrane
perinuclear region of cytoplasm
Biological process MAPK cascade
activation of MAPKK activity
positive regulation of protein phosphorylation
endocytosis
apoptotic process
induction of apoptosis
chemotaxis
cell cycle arrest
signal transduction
cell surface receptor signaling pathway
epidermal growth factor receptor signaling pathway
small GTPase mediated signal transduction
Ras protein signal transduction
synaptic transmission
axon guidance
blood coagulation
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
insulin receptor signaling pathway
visual learning
fibroblast growth factor receptor signaling pathway
organ morphogenesis
negative regulation of gene expression
actin cytoskeleton organization
positive regulation of cell migration
mitotic cell cycle G1/S transition checkpoint
regulation of synaptic transmission, GABAergic
positive regulation of Rac GTPase activity
negative regulation of Rho GTPase activity
positive regulation of Rac protein signal transduction
social behavior
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of DNA replication
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
nerve growth factor receptor signaling pathway
regulation of long-term neuronal synaptic plasticity
positive regulation of epithelial cell proliferation
leukocyte migration
striated muscle cell differentiation
positive regulation of ERK1 and ERK2 cascade
positive regulation of wound healing
cellular senescence
positive regulation of ruffle assembly
positive regulation of actin cytoskeleton reorganization
positive regulation of miRNA metabolic process
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 3265 15461 Ensembl ENSG00000174775 ENSMUSG00000025499 UniProt P01112 Q61411 RefSeq (mRNA) NM_001130442.1 NM_001130443.1 RefSeq (protein) NP_001123914.1 NP_001123915.1 Location (UCSC) Chr 11:
0.53 – 0.54 Mb Chr 7:
141.19 – 141.19 Mb PubMed search

GTPase HRas also known as transforming protein p21 is an enzyme that in humans is encoded by the HRAS gene. The HRAS gene is located on the short (p) arm of chromosome 11 at position 15.5, from base pair 522,241 to base pair 525,549.

Read more about HRAS:  Function

Other articles related to "hras, hra":

Historical Records Of Australian Science
... The Historical Records of Australian Science (HRAS) is the journal of record for the history of science, pure and applied, in Australia and the southwest Pacific ... The HRAS began in 1966 as an irregular publication as the Records of the Australian Academy of Science, the present name being adopted in 1980 ... The HRAS is published by CSIRO Publishing ...
HRAS - Clinical Significance - Other Cancers
... Somatic mutations in the HRAS gene are probably involved in the development of several other types of cancer ... These mutations lead to an HRAS protein that is always active and can direct cells to grow and divide without control ... Recent studies suggest that HRAS mutations may be common in thyroid and kidney cancers ...
FSA Debit Card - Background
... Though these cards can be issued with HRAs and HSAs as well as FSAs, the FSA is the oldest and most common of these accounts therefore, for ... these cards, whether tied to medical FSAs, HRAs or HSAs ... The rest of this article deals only with FSA debit cards used with medical FSAs, HRAs or HSAs.) HRAs, which were introduced later, technically don't involve "double-dippi ...
Health Risk Assessment - HRA Delivery
... The delivery of HRAs has changed over the years in conjunction with advances in technology ... on-site workplace health promotion sessions, HRAs are now most commonly implemented online ... The advantages of online HRAs include Tailoring – online HRAs can adapt content based on an individual’s answers to the HRA questionnaire to provide a personalised, relevant ...
Costello Syndrome - Genetics
... Costello syndrome is caused by any of at least five different mutations in the HRAS gene on chromosome 11 ... It remains unclear how mutations in HRAS cause other features of Costello syndrome, but many of the signs and symptoms may result from cell overgrowth and abnormal cell division ... HRAS is a proto-oncogene in which somatic mutations in healthy people can contribute to cancer ...