History of Molecular Evolution

The history of molecular evolution starts in the early 20th century with "comparative biochemistry", but the field of molecular evolution came into its own in the 1960s and 1970s, following the rise of molecular biology. The advent of protein sequencing allowed molecular biologists to create phylogenies based on sequence comparison, and to use the differences between homologous sequences as a molecular clock to estimate the time since the last common ancestor. In the late 1960s, the neutral theory of molecular evolution provided a theoretical basis for the molecular clock, though both the clock and the neutral theory were controversial, since most evolutionary biologists held strongly to panselectionism, with natural selection as the only important cause of evolutionary change. After the 1970s, nucleic acid sequencing allowed molecular evolution to reach beyond proteins to highly conserved ribosomal RNA sequences, the foundation of a reconceptualization of the early history of life.

Read more about History Of Molecular EvolutionEarly History, The "molecular Wars", The Neutral Theory of Molecular Evolution, Microbial Phylogeny

Other articles related to "molecular, history of molecular evolution, molecular evolution, history":

Molecular Term Symbol
... In molecular physics, the molecular term symbol is a shorthand expression of the group representation and angular momenta that characterize the state ... which is an eigenstate of the electronic molecular Hamiltonian ... to any exact symmetry of the electronic molecular Hamiltonian ...
History Of Molecular Evolution - Microbial Phylogeny
... While early work in molecular evolution focused on readily sequenced proteins and relatively recent evolutionary history, by the late 1960s some molecular ... Carl Woese, a molecular biologist whose earlier work was on the genetic code and its origin, began using small subunit ribosomal RNA to reclassify ... Work on microbial phylogeny also brought molecular evolution closer to cell biology and origin of life research ...
Journal Of Molecular Biology
... The Journal of Molecular Biology is a peer-reviewed scientific journal published weekly by Elsevier ... research concerning studies of organisms or their components at the molecular level ...
Molecularity
... Molecularity in chemistry is the number of colliding molecular entities that are involved in a single reaction step ... A reaction involving one molecular entity is called unimolecular ... A reaction involving two molecular entities is called bimolecular ...

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