EPRS

EPRS

Identifiers Symbols EPRS; EARS; GLUPRORS; PARS; QARS; QPRS External IDs OMIM: 138295 MGI: 97838 HomoloGene: 5870 ChEMBL: 3873 GeneCards: EPRS Gene EC number 6.1.1.17 6.1.1.15, 6.1.1.17

Gene Ontology
Molecular function	• glutamate-tRNA ligase activity • proline-tRNA ligase activity • protein binding • ATP binding • RNA stem-loop binding
Cellular component	• cytoplasm • cytosol • ribonucleoprotein complex
Biological process	• tRNA aminoacylation for protein translation • glutamyl-tRNA aminoacylation • prolyl-tRNA aminoacylation • protein complex assembly • gene expression • negative regulation of translation • cellular response to interferon-gamma
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2058 107508 Ensembl ENSG00000136628 ENSMUSG00000026615 UniProt P07814 Q8CGC7 RefSeq (mRNA) NM_004446 NM_029735 RefSeq (protein) NP_004437 NP_084011 Location (UCSC) Chr 1:
220.14 – 220.22 Mb Chr 1:
185.36 – 185.43 Mb PubMed search

Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.