Ebna

Some articles on ebna:

EPV - Virology - Protein/genes
... Protein/gene/antigen Stage Description EBNA-1 latent+lytic EBNA-1 protein binds to a replication origin (oriP) within the viral genome and mediates replication and partitioning of the ... EBNA-2 latent+lytic EBNA-2 is the main viral transactivator ... EBNA-3 latent+lytic These genes also bind the host RBP-Jκ protein ...
EPV - Virology - Latent Antigens
... The genes are ordered EBNA-LP/EBNA-2/EBNA-3A/EBNA-3B/EBNA-3C/EBNA-1 within the genome ... The initiation codon of the EBNA-LP coding region is created by an alternate splice of the nuclear protein transcript ... In the absence of this initiation codon, EBNA-2/EBNA-3A/EBNA-3B/EBNA-3C/EBNA-1 will be expressed depending on which of these genes is alternatively spliced into the transcript ...
USP7 - Association With Herpesviruses
... More recently, an interaction between USP7 and the EBNA1 protein of Epstein-Barr virus (EBV) (another herpesvirus) was also discovered ... This interaction is particularly interesting given the oncogenic potential (potential to cause cancer) of EBV, which is associated with several human cancers ...
EBV Nuclear Antigen 2
... EBNA-2 is the main viral transactivator, switching transcription from the Wp promoters initially used after infection to the Cp promoter ... Together with EBNA-3C, it also activates the LMP-1 promoter ... EBNA-2 is essential for EBV-mediated growth transformation ...