CD117 is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. Altered forms of this receptor may be associated with some types of cancer. CD117 is a receptor tyrosine kinase type III, which binds to stem cell factor (a substance that causes certain types of cells to grow), also known as "steel factor" or "c-kit ligand". When this receptor binds to stem cell factor (SCF) it forms a dimer that activates its intrinsic tyrosine kinase activity, that in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell. Signalling through CD117 plays a role in cell survival, proliferation, and differentiation.
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Other articles related to "function":
... differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original function is retrieved ... allows one to compute integrals by using an antiderivative of the function to be integrated ...
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance ... Just as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the double ... same volume can be obtained via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between the ...
Famous quotes containing the word function:
“My function in life is not to be a politician in Parliament: it is to get something done.”
—Bernadette Devlin (b. 1947)
“Of all the inhabitants of the inferno, none but Lucifer knows that hell is hell, and the secret function of purgatory is to make of heaven an effective reality.”
—Arnold Bennett (18671931)
“To look backward for a while is to refresh the eye, to restore it, and to render it the more fit for its prime function of looking forward.”
—Margaret Fairless Barber (18691901)