Cav1.2

Cav1.2

Identifiers Symbols CACNA1C; CACH2; CACN2; CACNL1A1; CCHL1A1; CaV1.2; LQT8; TS External IDs OMIM: 114205 MGI: 103013 HomoloGene: 55484 IUPHAR: Ca_v1.2 ChEMBL: 1940 GeneCards: CACNA1C Gene

Gene Ontology
Molecular function	• voltage-gated calcium channel activity • protein binding • calmodulin binding • protein domain specific binding • metal ion binding • alpha-actinin binding • protein phosphatase 2A binding
Cellular component	• cytoplasm • plasma membrane • voltage-gated calcium channel complex • postsynaptic density • integral to membrane • Z disc • T-tubule • neuronal cell body
Biological process	• energy reserve metabolic process • elevation of cytosolic calcium ion concentration • axon guidance • small molecule metabolic process • regulation of insulin secretion • calcium ion transport into cytosol
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 775 12288 Ensembl ENSG00000151067 ENSMUSG00000051331 UniProt Q13936 Q01815 RefSeq (mRNA) NM_000719.6 NM_001159533.1 RefSeq (protein) NP_000710.5 NP_001153005.1 Location (UCSC) Chr 12:
2.08 – 2.8 Mb Chr 6:
118.59 – 118.78 Mb PubMed search

Calcium channel, voltage-dependent, L type, alpha 1C subunit (also known as Ca_v1.2) is a protein that in humans is encoded by the CACNA1C gene. Ca_v1.2 is a subunit of L-type voltage-dependent calcium channel.