Bloodstone may refer to:
- Bloodstone (band), an R&B, soul and funk band
- Bloodstone, a 1972 album of Bloodstone
- James Bond 007: Blood Stone, a 2010 James Bond video game
- Ulysses Bloodstone, fictional comic character
- Elsa Bloodstone, fictional comic book character, the daughter of Ulysses Bloodstone
- Bloodstone (1988 film), a 1988 action/comedy film
- Bloodstone (2009 film), a 2009 horror film
- Bloodstone: An Epic Dwarven Tale, a 1993 video game by Mindcraft Software, Inc.
- Bloodstone: Subspecies II, a 1993 horror film
- "Bloodstone", a song by Judas Priest from the 1982 album Screaming for Vengeance
- "Bloodstone", a song by Amon Tobin from the 2007 album Foley Room
- "Bloodstone", a novel by Karl Edward Wagner, featuring Kane the Mystic Swordsman
Bloodstone may also be:
- Heliotrope (mineral), also known as bloodstone, a form of chalcedony
- Operation Bloodstone, a CIA recruitment program for former German officers and diplomats who could be used in the covert war against the Soviet Union.
- A item in the game Defense of the Ancients and Dota 2