Binding Sites

Some articles on binding sites, binding, site:

Ch IP-on-chip
... Specifically, it allows the identification of the cistrome, sum of binding sites, for DNA-binding proteins on a genome-wide basis ... analysis can be performed to determine the locations of binding sites for almost any protein of interest ... The goal of ChIP-on-chip is to localize protein binding sites that may help identify functional elements in the genome ...
Hill Equation (biochemistry)
... In biochemistry, the binding of a ligand to a macromolecule is often enhanced if there are already other ligands present on the same macromolecule (this is known as Cooperative ... concentration it is used in determining the degree of cooperativeness of the ligand binding to the enzyme or receptor ... by Archibald Hill in 1910 to describe the sigmoidal O2 binding curve of hemoglobin ...
P-type ATPase - Structure - Structure of SERCA1a
... of a cytoplasmic section and a transmembrane section with two Ca2+ binding sites ... section has ten transmembrane helices (M1-M10), with the two Ca2+ binding sites located near the midpoint of the bilayer ... The binding sites are formed by side-chains and backbone carbonyls from M4, M5, M6, and M8 ...
Cis-regulatory Module
... Regulatory elements are binding sites for transcription factors, which are involved in gene regulation ... non-random clusters at their specified target site that contain transcription factor binding sites ... modules as a DNA sequence with transcription factor binding sites which are clustered into modular structures, including -but not limited to- locus control regions, promoters, enhancers, silencers ...
Schild Regression For Ligand Binding
... the effect, the effect is, in essence, a result of the binding kinetics so, in order to illustrate the mechanism, ligand binding is used ... inverse, the affinity constant (Kaff = k1/k-1) A better binding means an increase of binding affinity ... The equation for simple ligand binding to a single homogeneous receptor is This is the Hill-Langmuir equation, which is practically the Hill equation (biochemistry) described for the agonist binding ...

Famous quotes containing the word binding:

    What is lawful is not binding only on some and not binding on others. Lawfulness extends everywhere, through the wide-ruling air and the boundless light of the sky.
    Empedocles 484–424 B.C., Greek philosopher. The Presocratics, p. 142, ed. Philip Wheelwright, The Bobbs-Merrill Co., Inc. (1960)