AIF1
| Gene Ontology | |
|---|---|
| Molecular function | • molecular_function • calcium ion binding • actin filament binding |
| Cellular component | • phagocytic cup • nucleus • cytoplasm • cytosol • actin filament • lamellipodium • ruffle membrane • perikaryon • perinuclear region of cytoplasm |
| Biological process | • microglial cell activation • positive regulation of protein phosphorylation • phagocytosis, engulfment • inflammatory response • negative regulation of gene expression • positive regulation of muscle hyperplasia • Rac protein signal transduction • actin filament polymerization • cellular response to extracellular stimulus • cellular response to hormone stimulus • positive regulation of T cell proliferation • negative regulation of apoptotic process • positive regulation of nitric oxide biosynthetic process • positive regulation of smooth muscle cell proliferation • negative regulation of smooth muscle cell proliferation • response to axon injury • actin filament bundle assembly • response to electrical stimulus • cellular response to interferon-gamma • negative regulation of smooth muscle cell chemotaxis • positive regulation of smooth muscle cell chemotaxis • positive regulation of monocyte chemotaxis • ruffle assembly • positive regulation of G1/S transition of mitotic cell cycle • positive regulation of T cell migration |
| Sources: Amigo / QuickGO | |
31.58 – 31.58 Mb
35.17 – 35.18 Mb
Allograft inflammatory factor 1 (AIF-1) also known as ionized calcium-binding adapter molecule 1 (IBA1) is a protein that in humans is encoded by the AIF1 gene.
Read more about AIF1: Gene, Function