What is neural tube?

  • (noun): A tube of ectodermal tissue in the embryo from which the brain and spinal cord develop.

Neural Tube

In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system.

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Some articles on neural tube:

Neural Tube - Dorsal-ventral Patterning
... The neural tube becomes patterned along the dorsal-ventral axis to establish defined compartments of neural progenitor cells, which will give rise to distinct classes of neurons ... to provide positional information to the neural progenitor cells include Fibroblast growth factors (FGF) and Retinoic Acid ... cell types are established during early neural tube development, these include the floor plate cells, which form at the ventral midline during the neural ...
ASCL1 - Role in Neuronal Commitment
... Development of the vertebrate nervous system begins when the neural tube forms in the early embryo ... The neural tube eventually gives rise to the entire nervous system, but first neuroblasts must differentiate from the neuroepithelium of the tube ... Differentiation of the neuroblast begins when the cells of the neural tube express Asc and thus upregulate the expression of Delta, a protein essential to the lateral inhibition ...
MOMS Study
... is a developmental congenital disorder caused by the incomplete closing of the embryonic neural tube ... Other neural tube defects include anencephaly, a condition in which the portion of the neural tube that will become the cerebrum does not close, and ...
Neural Fold - Folding Mechanism - Mechanism
... In order to allow for the growth of precursor neural tissues, as opposed to precursor bone or cartilage tissues, BMP expression is decreased in the neural plate, specifically along the medial line ... produced from the genes Noggin and Chordin inhibit these BMPs, and subsequently allow neural commitment genes, like Sox, to be expressed ... expression of these cells, furthering them along the path of neural cell commitment ...
... Neuroectoderm (or neural ectoderm or neural tube epithelium) is the term for ectoderm which receives Bone Morphogenetic Protein-inhibiting signals from proteins such as noggin ... of development transformation into the neural plate, transformation into the neural groove (with associated neural folds), and transformation into ... After formation of the tube, the brain forms into three sections the hindbrain, the midbrain, and the forebrain ...

Famous quotes containing the word tube:

    One of the great natural phenomena is the way in which a tube of toothpaste suddenly empties itself when it hears that you are planning a trip, so that when you come to pack it is just a twisted shell of its former self, with not even a cubic millimeter left to be squeezed out.
    Robert Benchley (1889–1945)