What is dna methylation?

DNA Methylation

DNA methylation is a biochemical process that is important for normal development in higher organisms. It involves the addition of a methyl group to the 5 position of the cytosine pyrimidine ring or the number 6 nitrogen of the adenine purine ring (cytosine and adenine are two of the four bases of DNA). This modification can be inherited through cell division.

Read more about Dna Methylation.

Some articles on dna methylation:

Methylated DNA Immunoprecipitation - Downstream Bioinformatics Analysis
... The DNA methylation level estimations can be confounded by varying densities of methylated CpG sites across the genome when observing data generated by MeDIP ... developed a tool to estimate absolute methylation levels from data generated by MeDIP by modeling the density of methylated CpG sites ... This tool is called Bayesian tool for methylation analysis (Batman) ...
DNA Methylation - Computational Prediction
... DNA methylation can also be detected by computational models through sophisticated algorithms and methods ... Computational models can facilitate the global profiling of DNA methylation across chromosomes, and often times such models are faster and cheaper to perform than biological assays ... with biological assay, these methods greatly facilitate the DNA methylation analysis ...
Epigenetics - Epigenetic Effects in Humans - Cancer and Developmental Abnormalities - DNA Methylation in Cancer
... DNA methylation is an important regulator of gene transcription and a large body of evidence has demonstrated that aberrant DNA methylation is associated with unscheduled gene silencing, and the genes ... DNA methylation is essential during embryonic development, and in somatic cells, patterns of DNA methylation are in general transmitted to daughter cells with a high fidelity ... Aberrant DNA methylation patterns have been associated with a large number of human malignancies and found in two distinct forms hypermethylation and hypomethylation compared to normal ...
Computational Epigenetics - Epigenetics Databases
... MethDB Contains information on 19,905 DNA methylation content data and 5,382 methylation patterns for 48 species, 1,511 individuals, 198 tissues and cell lines and 79 phenotypes ... REBASE Contains over 22,000 DNA methyltransferases genes derived from GenBank ... MeInfoText Contains gene methylation information across 205 human cancer types ...
1992 GeneCards DNMT3A Gene EC number Gene Ontology Molecular function • DNA binding • chromatin binding • DNA (cytosine-5-)-methyltransferase ... CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation ... Studies in mice have demonstrated that DNA methylation is required for mammalian development ...

Famous quotes containing the word dna:

    Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.
    William Gibson (b. 1948)