Substrate Molecules

Enzyme Kinetics - Non-Michaelis–Menten Kinetics
... Some enzymes produce a sigmoid v by plot, which often indicates cooperative binding of substrate to the active site ... This means that the binding of one substrate molecule affects the binding of subsequent substrate molecules ... of cooperation is similar to that of hemoglobin, with binding of substrate to one active site altering the affinity of the other active sites for substrate molecules ...