Query Sequence

Some articles on sequence, sequences, query sequence:

Homology Modeling - Template Selection and Sequence Alignment
... The simplest method of template identification relies on serial pairwise sequence alignments aided by database search techniques such as FASTA and BLAST ... More sensitive methods based on multiple sequence alignment – of which PSI-BLAST is the most common example – iteratively update their position-specific scoring matrix to ... of potential templates and to identify better templates for sequences that have only distant relationships to any solved structure ...
Sequence Alignment - Pairwise Alignment - Word Methods
... where it is understood that a large proportion of the candidate sequences will have essentially no significant match with the query sequence ... Word methods identify a series of short, nonoverlapping subsequences ("words") in the query sequence that are then matched to candidate database sequences ... The relative positions of the word in the two sequences being compared are subtracted to obtain an offset this will indicate a region of alignment if multiple distinct words produce the same offset ...
Homology Modeling
... an atomic-resolution model of the "target" protein from its amino acid sequence and an experimental three-dimensional structure of a related homologous protein (the "template") ... protein structures likely to resemble the structure of the query sequence, and on the production of an alignment that maps residues in the query sequence to residues in the template sequence ... protein structures are more conserved than protein sequences amongst homologues, but sequences falling below a 20% sequence identity can have very different structure ...

Famous quotes containing the words sequence and/or query:

    It isn’t that you subordinate your ideas to the force of the facts in autobiography but that you construct a sequence of stories to bind up the facts with a persuasive hypothesis that unravels your history’s meaning.
    Philip Roth (b. 1933)

    Such condition of suspended judgment indeed, in its more genial development and under felicitous culture, is but the expectation, the receptivity, of the faithful scholar, determined not to foreclose what is still a question—the “philosophic temper,” in short, for which a survival of query will be still the salt of truth, even in the most absolutely ascertained knowledge.
    Walter Pater (1839–1894)