Mukaiyama Aldol Reaction

Some articles on aldol, reaction, aldol reaction, mukaiyama aldol reaction, mukaiyama aldol:

Aldol Condensation
... An aldol condensation is an organic reaction in which an enol or an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone, followed ... Aldol condensations are important in organic synthesis, providing a good way to form carbon–carbon bonds ... The Robinson annulation reaction sequence features an aldol condensation the Wieland-Miescher ketone product is an important starting material for many organic ...
Aldol - Discovery
... The Aldol reaction was discovered in 1872 by French chemist Charles-Adolphe Wurtz ... The Wurtz reaction, where two alkyl halides are treated with sodium to form a new carbon−carbon bond, is no longer considered synthetically useful ... Alexander Borodin is also credited with the discovery of the Aldol reaction together with Wurtz ...
Modern Variations and Methods - Mukaiyama Aldol Reaction
... The Mukaiyama aldol reaction is the nucleophilic addition of silyl enol ethers to aldehydes catalyzed by a Lewis acid such as boron trifluoride or titanium ... The Mukaiyama aldol reaction does not follow the Zimmerman-Traxler model ... The analogous vinylogous Mukaiyama aldol process can also be rendered catalytic and asymmetric ...
Aldol Reaction - Evans' Oxazolidinone Chemistry
... Since the aldol addition reaction creates two new stereocenters, up to four stereoisomers may result ... The pre-existing chirality from the auxiliary is then transferred to the aldol adduct by performing a diastereoselective aldol reaction ... Upon subsequent removal of the auxiliary, the desired aldol stereoisomer is revealed ...
Mukaiyama Aldol Addition
... The Mukaiyama aldol addition is an organic reaction and a type of aldol reaction between a silyl enol ether and an aldehyde catalyzed by a Lewis acid ... This choice of reactants allows for a crossed aldol reaction between an aldehyde and a ketone or a different aldehyde without self-condensation of the aldehyde ... For this reason the reaction is used extensively in organic synthesis ...

Famous quotes containing the word reaction:

    The excessive increase of anything often causes a reaction in the opposite direction.
    Plato (c. 427–347 B.C.)