Lipid Peroxidation

Lipid peroxidation refers to the oxidative degradation of lipids. It is the process in which free radicals "steal" electrons from the lipids in cell membranes, resulting in cell damage. This process proceeds by a free radical chain reaction mechanism. It most often affects polyunsaturated fatty acids, because they contain multiple double bonds in between which lie methylene -CH2- groups that possess especially reactive hydrogens. As with any radical reaction, the reaction consists of three major steps: initiation, propagation, and termination.

Read more about Lipid Peroxidation:  Initiation, Propagation, Hazards, Tests

Other articles related to "lipid peroxidation, lipid":

Cephaloridine - Adverse Effects - Metabolism
... This process is preceded by the lipid peroxidation ... of a reactive intermediate, a free radical and stimulation of lipid peroxidation, lead to peroxidative damage to cell membranes and mitochondria ... Both lipid peroxidation and oxidative stress can cause membrane damage ...
Lipid Peroxidation - Tests
... are available for the quantification of the end-products of lipid peroxidation, to be specific, malondialdehyde (MDA) ... are other sources of malondialdehyde, so this test is not completely specific for lipid peroxidation ...
TBARS
... substances - TBARS - are formed as a byproduct of lipid peroxidation (i.e ... sample, as well as malondialdehyde generated from lipid hydroperoxides by the hydrolytic conditions of the reaction ... the decomposition of certain primary and secondary lipid peroxidation products ...
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... Aluminum toxicity causes an increase in lipid peroxidation, with most damage occurring in the brain ... A recent review of studies shows pinoline and melatonin to be effective at reducing the lipid peroxidation ... the production of free radicals which in turn cause lipid peroxidation ...