Hygiene Hypothesis

In medicine, the hygiene hypothesis states that a lack of early childhood exposure to infectious agents, symbiotic microorganisms (e.g., gut flora or probiotics), and parasites increases susceptibility to allergic diseases by suppressing natural development of the immune system. Because of this we fail to induce a Th1 polarized response early in life so as we grow up we are more prone to developing Th2 induced disease. The rise of autoimmune diseases and acute lymphoblastic leukemia in young people in the developed world has also been linked to the hygiene hypothesis.

There is some evidence that autism may be caused by an immune disease; One publication speculated that the lack of early childhood exposure could be a cause of autism.

Read more about Hygiene HypothesisHistory, Mechanism of Action, Breadth of The Hypothesis, Supporting Evidence, Helminthic Therapy, Alternative Hypotheses

Other articles related to "hygiene hypothesis, hypothesis":

Hygiene Hypothesis - Alternative Hypotheses
... conditions related to Strachan's original version of the hygiene hypothesis, such as atopy and asthma, the pool chlorine hypothesis was proposed by Albert Bernard and his colleagues ...
Pool Chlorine Hypothesis - Relation To The Hygiene Hypothesis
... results, Bernard and his colleagues have suggested that the hygiene hypothesis still lacks a close causal link with asthma, and that the hygiene hypothesis might be most relevant for ...
Asthma - Causes - Environmental - Hygiene Hypothesis
... for the cause of the increase in asthma prevalence worldwide is the "hygiene hypothesis" —that the rise in the prevalence of allergies and asthma is a direct and unintended ... and thus the immune system (as described by the hygiene hypothesis) ... The hygiene hypothesis is a hypothesis about the cause of asthma and other allergic disease, and is supported by epidemiologic data for asthma ...

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    Oversimplified, Mercier’s Hypothesis would run like this: “Wit is always absurd and true, humor absurd and untrue.”
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