Histamine Receptor

Histamine Receptor

The histamine receptors are a class of G protein-coupled receptors with histamine as their endogenous ligand.

There are four known histamine receptors:

  • H1 receptor
  • H2 receptor
  • H3 receptor
  • H4 receptor

Read more about Histamine Receptor:  Comparison

Other articles related to "histamine receptor, histamine receptors, receptor, receptors, histamine":

Histamine Receptor - Comparison
... Histamine receptors Receptor Mechanism Function Antagonists H1 Gq ileum contraction modulate circadian cycle itching systemic vasodilatation bronchoconstriction (allergy-induced asthma ... H4-receptor antagonists Thioperamide JNJ 7777120 There are several splice variants of H3 present in various species ... Though all of the receptors are 7-transmembrane g protein coupled receptors, H1 and H2 are quite different from H3 and H4 in their activities ...
Histamine - Mechanism of Action
... Histamine exerts its actions by combining with specific cellular histamine receptors ... The four histamine receptors that have been discovered in humans and animals are designated H1 through H4, and are all G protein-coupled receptors (GPCR) ... Histamine biology is a series of weak interactions ...
H2 Antagonist - History and Development
... Cimetidine was the prototypical histamine H2-receptor antagonist from which the later members of the class were developed ... Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion ... In 1964 it was known that histamine stimulated the secretion of stomach acid, but also that traditional antihistamines had no effect on acid production ...
Histamine H1 Receptor
... Gene Gene Ontology Molecular function • G-protein coupled receptor activity • histamine receptor activity • histamine binding Cellular component • nucleus • nucleolus ... This receptor, which is activated by the biogenic amine histamine, is expressed throughout the body, to be specific, in smooth muscles, on vascular endothelial cells, in the heart ... The H1 receptor is linked to an intracellular G-protein (Gq) that activates phospholipase C and the phosphatidylinositol (PIP2) signaling pathway ...

Famous quotes containing the word receptor:

    The disinterest [of my two great-aunts] in anything that had to do with high society was such that their sense of hearing ... put to rest its receptor organs and allowed them to suffer the true beginnings of atrophy.
    Marcel Proust (1871–1922)